Wrong Going Ons.
There is a lot going wrong in this photo (of Lot & his daughters), and don't let dog breeders try to tell you any different.
In-breeding (short for incestuous breeding) will lead to genetic or health problems, especially in domestic animal where Nature doesn't cull the weak.
In cats, inbreeding seems to cause health problems sooner, sometimes after the first inbred generation.
In dogs, breeders have done inbreeding longer. Maybe it would have been better if the ill effects had shown up right away.
Now instead of one family of weak inbred kittens, we have whole breeds of dogs with problems.
Incest has Lot's problem, and lots of problems.